berntpopp

Enables querying of per-residue missense tolerance, Pfam domain annotations, and variant counts for human transcripts by wrapping the MetaDome web service. Prov

MCP server that provides tools for querying the Human Phenotype Ontology (HPO) including term lookup, hierarchy exploration, cross-ontology mappings, and gene-p

An MCP server that enables querying rare-disease data from Orphanet, including disease nomenclature, cross-references, classifications, gene associations, HPO p

Federates 13 gene-related MCP backends (gnomAD, GTEx, etc.) behind a single Streamable HTTP endpoint with collision-free namespacing and search-based tool disco

An MCP server that grounds protein research in the UniProt SPARQL endpoint, providing tools for querying proteins, sequences, variants, diseases, and more via i

An MCP server that provides mouse genetics data from Mouse Genome Informatics (MGI), enabling LLM agents to query markers, mutations, alleles, phenotypes, and d

Grounds gene-nomenclature work in the HUGO Gene Nomenclature Committee (HGNC) dataset, enabling resolution of gene symbols and IDs to canonical HGNC identifiers

MCP server that provides tools to query harmonized gene-disease validity data from the Gene Curation Coalition, supporting consensus and conflict detection for

Enables querying ClinGen curated evidence for gene-disease validity, dosage, actionability, and variant pathogenicity via MCP tools.

MCP gateway federating 21 biomedical MCP servers — gnomAD, ClinVar, HPO, UniProt, Ensembl VEP, PanelApp and more — behind one Streamable-HTTP endpoint, with col

MCP server for the Mondo Disease Ontology: disease term lookup, the is_a hierarchy, and cross-ontology mapping across OMIM, Orphanet, DOID, NCIT, UMLS and MeSH.

MCP server for STRING v12: protein–protein association networks, interaction partners, and functional enrichment analysis — as typed tools for LLM agents.

MCP server for the GTEx Portal: tissue-specific gene expression — median and per-sample TPM, top expressed genes per tissue, and gene/transcript annotation — as

MCP server for SpliceAI Lookup (Broad Institute): SpliceAI, Pangolin and SpliceAI-10k splice-impact predictions for variants, plus an Ensembl VEP-backed variant

MCP server for AutoPVS1: automated ACMG PVS1 loss-of-function evidence for sequence variants and copy-number variants — variant interpretation as typed tools fo

MCP server for MaveDB: quantitative variant-effect scores from Multiplexed Assays of Variant Effect (MAVE) and deep mutational scanning — functional evidence as