Guide to Pharmacology

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Peer-reviewed pharmacological targets and ligands from the IUPHAR/BPS Guide to PHARMACOLOGY.

автор: pipeworx-io

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Описание

Peer-reviewed pharmacological targets and ligands from the IUPHAR/BPS Guide to PHARMACOLOGY.

README

IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb) MCP — keyless.

Part of Pipeworx — an MCP gateway connecting AI agents to 1394+ live data sources.

Tools

Tool	Description
`search_ligands`	Search the Guide to PHARMACOLOGY (IUPHAR/BPS) — an expert-curated pharmacology database — for drug ligands by name. Returns matching ligands with their GtoPdb ligand id, type (e.g. Synthetic organic, Peptide, Antibody, Metabolite), and approval status. Use the returned ligand id with ligand_interactions to find which protein targets it acts on. Keyless. Complements ChEMBL/DrugBank.
`search_targets`	Search the Guide to PHARMACOLOGY (IUPHAR/BPS) — an expert-curated pharmacology database — for protein targets by name. Returns matching targets with their GtoPdb target id, abbreviation, and type (e.g. GPCR, CatalyticReceptor, Enzyme, Transporter). Use the returned target id with target_interactions to find ligands that bind it. Keyless. Complements ChEMBL/DrugBank.
`target_interactions`	List the quantitative ligand interactions for a protein target in the Guide to PHARMACOLOGY (IUPHAR/BPS). Given a GtoPdb target id (from search_targets), returns the ligands acting on it with interaction type (Agonist/Antagonist/Inhibitor/etc.), action, and binding affinity (e.g. pKi/pIC50). Keyless.
`ligand_interactions`	List the quantitative target interactions for a drug ligand in the Guide to PHARMACOLOGY (IUPHAR/BPS). Given a GtoPdb ligand id (from search_ligands), returns the protein targets it acts on with interaction type (Agonist/Antagonist/Inhibitor/etc.), action, and binding affinity (e.g. pKi/pIC50). Keyless.

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "guidetopharmacology": {
      "url": "https://gateway.pipeworx.io/guidetopharmacology/mcp"
    }
  }
}

Or connect to the full Pipeworx gateway for access to all 1394+ data sources:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English:

ask_pipeworx({ question: "your question about Guidetopharmacology data" })

The gateway picks the right tool and fills the arguments automatically.

License

MIT

from github.com/pipeworx-io/mcp-guidetopharmacology

Установить Guide to Pharmacology в Claude Desktop, Claude Code, Cursor

Рекомендуется · одна команда, все IDE

unyly install guide-to-pharmacology

Ставит в Claude Desktop, Claude Code, Cursor и VS Code — сам разбирается с npx, uvx и сборкой из исходников.

Впервые? Поставь CLI: curl -fsSL https://unyly.org/install | sh

Или настроить вручную

Выполни в терминале:

claude mcp add guide-to-pharmacology -- npx -y @pipeworx/mcp-guidetopharmacology

Пошаговые гайды: как установить Guide to Pharmacology

Установить Guide to Pharmacology в Claude Desktop Установить Guide to Pharmacology в Claude Code Установить Guide to Pharmacology в Cursor Установить Guide to Pharmacology в VS Code

FAQ