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Provides access to AlphaFold predicted protein 3D structures from EBI, enabling retrieval of prediction metadata, summaries, annotations, and UniProt data.
Provides access to AlphaFold predicted protein 3D structures from EBI, enabling retrieval of prediction metadata, summaries, annotations, and UniProt data.
AlphaFold DB MCP — predicted protein structures.
Part of Pipeworx — an MCP gateway connecting AI agents to 965+ live data sources.
| Tool | Description |
|---|---|
prediction |
Full prediction metadata + structure file URLs (PDB, CIF, PAE). |
summary |
Short summary for a prediction (organism, sequence, mean pLDDT). |
annotations |
Sequence-level annotations (e.g. MUTAGEN, LOW_CONFIDENCE_REGIONS). |
uniprot |
Fetch AlphaFold structure prediction metadata (PDB/CIF/PAE download URLs, pLDDT scores) by UniProt accession (e.g. "P00533"); equivalent to prediction but takes uniprot_id explicitly. |
Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):
{
"mcpServers": {
"alphafold": {
"url": "https://gateway.pipeworx.io/alphafold/mcp"
}
}
}
Or connect to the full Pipeworx gateway for access to all 965+ data sources:
{
"mcpServers": {
"pipeworx": {
"url": "https://gateway.pipeworx.io/mcp"
}
}
}
Instead of calling tools directly, you can ask questions in plain English:
ask_pipeworx({ question: "your question about Alphafold data" })
The gateway picks the right tool and fills the arguments automatically.
MIT
Run in your terminal:
claude mcp add mcp-alphafold -- npx Yes, Alphafold MCP is free — one-click install via Unyly at no cost.
No, Alphafold runs without API keys or environment variables.
A hosted option is available: Unyly runs the server in the cloud, no local setup required.
Open Alphafold on unyly.org, pick your client tab (Claude Desktop, Claude Code, Cursor) and press Install — the config is generated automatically, no JSON editing.
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Security
Low riskAutomated heuristic from public metadata — not a security guarantee.