Opentargets

Open Targets MCP — disease/target/drug knowledge graph.

Part of Pipeworx — an MCP gateway connecting AI agents to 673+ live data sources.

Tools

Tool	Description
target	Target (gene) profile by Ensembl id.
disease	Disease profile by EFO id.
drug	Drug profile by ChEMBL id.
search	Platform search across diseases/targets/drugs.
target_associations	Top disease associations for a target.
disease_associations	Top target associations for a disease.
target_known_drugs	Drugs clinically tested against a target.

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "opentargets": {
      "url": "https://gateway.pipeworx.io/opentargets/mcp"
    }
  }
}

Or connect to the full Pipeworx gateway for access to all 673+ data sources:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English:

ask_pipeworx({ question: "your question about Opentargets data" })

The gateway picks the right tool and fills the arguments automatically.

More

• All tools and guides
• pipeworx.io

License

MIT